GROWTH COMPARISONS OF STREPTOMYCIN-SENSITIVE AND STREPTOMYCIN-RESISTANT MICROCOCCUS PYOGENES VAR. AUREUS

A study of streptomycin resistance in Micrococcus pyogenes var. aureus.

There are two theories as to the origin of microbial resistance to toxic agents; namely, (a) resistance is the result of some interaction between microorganism and toxic agent, resulting in an increased ability of the cell to withstand the deleterious effects of the drug, and (b) the toxic agent merely serves to select from the total population pre-existing mutant cells that are resistant. For ...

Fastness of Micrococcus pyogenes var. aureus to subtilin and to combinations of subtilin and streptomycin.

Cell division in Micrococcus pyogenes var. aureus.

Recent progress in bacterial cytology has left no doubt as to the existence of a discrete nuclear body in bacterial cells. Numerous publications have appeared describing the appearance of apparent nuclear bodies in coccus forms, and descriptions of the activity of these bodies have been meticulously recorded. The literature on the nuclei of the cocci has been covered aptly by DeLamater and Wood...

A catalase negative Micrococcus pyogenes var. aureus.

of which has been shown to accelerate the conversion of citrulline to ornithine (Slade, Arch. Biochem. and Biophys., 42, 204, 1953). Studies using phosphate buffers indicated that carbon dioxide formation occurred optimally in the range pH 5.9-6.1 in the glucose-arginine mixture, which is in agreement with Slade's observation (Arch. Biochem. and Biophys., 42, 204, 1953). Lactic acid production ...

Accumulation of 14C-streptomycin by streptomycin-sensitive and streptomycin-resistant group H streptococci.

Three streptomycin-resistant mutants of group H streptococcus, strain Challis, were examined for ability to accumulate (14)C-streptomycin. Although the mutants exhibited different levels of transformation, only the streptomycin-sensitive parent Challis strain accumulated significant amounts of (14)C-streptomycin. It appears that impermeability to streptomycin does not necessarily result in redu...